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個人詳細資料

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姓名 Wenwei Lin
Office_Hour  
實驗室電話 (02) 77346200
辦公室電話 (02) 77346131
傳真 (02) 2932 4249
聯絡地址 （11677）No. 88, Sec. 4, Ting-Chow Rd, Taipei, Taiwan, 11677, R.O.C.
E-mail wenweilin@ntnu.edu.tw
實驗室網頁 http://www.chem.ntnu.edu.tw/~wwlin/index.htm
類別 Full-Time
職稱 Professor
研究領域 Synthetic Methodology, Asymmetric Organic Catalysis
學術專長 Organic Synthesis, Asymmetric Organic Catalysis
指導學生 Postdoc.: Dr. Lennart Moehlmann, Dr. Ganapuram Madhusudhan Reddy; Ph.D students: Yi-Ling Tsai, Yi-Ru Chen; Master students: Shu-Mei Yang, Shao-Hao Hong, Meng-Hsien Liu, Ming-Yu Hsiao, Chien-Yi Wang, Chi-Ting Ko, 張耕華, 謝鎧鴻, 林群凱, 王子平, 張慈修。
實驗室 Wenwei Lin - research group /

Academic Researches

  1. Journal Articles
    1. Fan, Y.-S.; Das, U.; Hsiao, M.-Y.; Liu, M.-S.; Lin, W.* "Chemoselective Intramolecular Wittig Reactions for the Synthesis of Oxazoles and Benzofurans” J. Org. Chem. 2014, accepted. 參考連結參考連結
    2. Jang, Y.-J.; Chen, Y.-S.; Lee, C.-J.; Chen, C.-H.; Lin, W.* "Base-Catalyzed Domino Double Michael Reactions of 1-Hydroxy-1,4-dien-3-ones and 2-Alkylidene Malononitirles: A Diastereoselective Route to Polysubstituted 4-Hydroxy-3-keto-cyclohex-3-ene” Synthesis 2014, DOI: 10.1055/s-0034-1379143. 參考連結參考連結
    3. Tsai, Y.-L.; Syu, S.; Yang, S.-M.; Das, U.; Fan, Y.-S.; Lee, C.-J.; Lin, W.* "Synthesis of Multi-Functional Alkenes via Wittig Reaction with a New-Type of Phosphorus Ylides” Tetrahedron 2014, 70, 5038-5045.
       參考連結參考連結
    4. Das, U.; Tsai, Y.-L.; Lin, W.* "Preparation of functionalized heteroaromatics using intramolecular Wittig reaction” Org. Biomol. Chem. 2014, 12, 4044-4050. (Perspective)  參考連結參考連結
    5. Lee, C.-J.; Sheu, C.-N.; Tsai, C.-C.; Wu, Z.-Z.; Lin, W.* "Direct  β-Acylation of 2-Arylidene-1,3-indandiones with Acyl Chlorides Catalyzed by Organophosphanes” Chem. Commun. 2014, 50, 5304-5306. (Featured in “Emerging investigators” issue 2014) 參考連結參考連結
    6. “Contributors to the Emerging Investigators Issue 2014”, Chem. Commun. 2014, 50, 5100-5114. 參考連結參考連結
    7. Lee, Y.-T.; Das, U.; Chen, Y.-R.; Lee, C.-J.; Chen, C.-H.; Yang, M.-C.; Lin, W.* "Enantioselective Synthesis of Coumarin Derivatives Catalyzed by Primary Amine” Adv. Synth. Catal. 2013, 355, 3154-3160. 參考連結參考連結
    8. Tsai, Y.-L.; Fan, Y.-S.; Lee, C.-J.; Huang, C.-H.; Das, U.; Lin, W.* "An Efficient Synthesis of Trisubstituted Oxazoles via Chemoselective O-Acylations and Intramolecular Wittig Reactions” Chem. Commun. 2013, 49, 10266-10268. 參考連結參考連結
    9.  Lee, Y.-T.; Lee, Y.-T.; Lee, C.-J.; Sheu, C.-N.; Lin, B.-Y.; Wang, J.-H.*; Lin, W.* "Chemoselective Synthesis of Tetrasubstituted Furans via Intramolecular Wittig Reactions: Mechanism and Theoretical Analysis” Org. Biomol. Chem. 2013, 11, 5156-5161. 參考連結參考連結
    10.  Tsai, Y.-L.; Das, U.; Syu, S.; Lee, C.-J.; Lin, W.* “Facile synthesis of functional tricyclic fused furans via intramolecular Wittig reactions” Eur. J. Org. Chem. 2013, 4634-4641. 參考連結參考連結
    11. Das, U.; Chen, Y.-R.; Tsai, Y.-L.; Lin, W.* “Organocatalytic enantioselective direct vinylogous Michael addition of r-substituted butenolides to 3-aroyl acrylates and 1,2-diaroylethylenes” Chem. Eur. J. 2013, 19, 7713-7717. 參考連結參考連結
    12. Wu, Z.-Z.; Jang, Y.-J.; Lee, C.-J.; Lee, Y.-T.; Lin, W.* “A Versatile and Practical Method for Regioselective Synthesis of Polysubstituted Furanonaphthoquinones” Org. Biomol. Chem. 2013, 11, 828-834. (HOT article) 參考連結參考連結
    13. Das, U.; Tsai, Y.-L.; Lin, W.* “An efficient organocatalytic enantioselective synthesis of spironitrocyclopropanes” Org. Biomol. Chem. 2013, 11, 44-47. (HOT communication) 參考連結參考連結
    14. Lee, Y.-T.; Jang, Y.-J.; Syu, S.; Chou, S.-C.; Lee, C.-J.; Lin, W.* “Preparation of Functional Benzofurans and Indoles via Chemoselective Intramolecular Wittig Reactions” Chem. Commun. 2012, 48, 8135-8137 參考連結參考連結
    15. Das, U.; Huang, C.-H.; Lin, W.* "Enantioselective synthesis of substituted pyrans via amine-catalyzed Michael addition and subsequent enolization/cyclisation" Chem. Commun. 2012, 48, 5590-5592. (Featured in “Organocatalysis” Web-themed issue) 參考連結參考連結
    16. Lee, C.-J.; Jang, Y.-J.; Wu, Z.-Z. ; Lin, W.* “Preparation of Functional Phosphorus Zwitterions from Activated Alkanes, Aldehydes, and Tributylphosphine: Synthesis of Polysubstituted Furo[3,2-c]coumarins” Org. Lett. 2012, 14, 1906-1909. 參考連結參考連結
    17. Jang, Y.-J.; Syu, S.; Jhang, Y.-W.; Lee, Y.-T.; Lee, C.-J.; Chen, K.-W.; Das, U.; Lin, W.* “Tandem three-component reactions of aldehyde, alkyl acrylate, and dialkylmalonate catalyzed by ethyl diphenylphosphine” Molecules 2012, 17, 2529-2541.
      參考連結參考連結
    18. Syu, S.; Huang, C.-H.; Chen, K.-W.; Lee, C.-J.; Das, U.; Jang, Y.-J.; Lin, W.* “Enantioselective organocatalytic Michael addition of ketones to alkylidene malonates” Chirality 2012, 24, 600-605.
      參考連結參考連結
    19. Jang, Y.-J.; Syu, S.; Chen, Y.-J.; Yang, M.-C.; Lin, W.* “Syntheses of Furo[3,4-c]coumarins and Related Furyl Coumarin Derivatives via Intramolecular Wittig Reactions” Org. Biomol. Chem. 2012, 10, 843-847.
      參考連結參考連結
    20. Syu, S.; Lee, Y.-T.; Jang, Y.-J.; Lin, W.* “Preparation of Functional Benzofurans, Benzothiophenes, and Indoles Using Ester, Thioester, and Amide via Intramolecular Wittig Reactions” Org. Lett. 2011, 13, 2970-2973.
      參考連結參考連結
    21. Syu, S.; Lee, Y.-T.; Jang, Y.-J.; Lin, W.* “Organocatalytic tandem three-component reaction of imine, alkyl vinyl ketone, and imide via aza-Baylis-Hillman reaction” J. Org. Chem. 2011, 76, 2888-2891.
      參考連結參考連結
    22. Chen, K.-W.; Syu, S.; Jang, Y.-J.; Lin, W.* “A facile approach to highly functional trisubstituted furans via intramolecular Wittig reactions” Org. Biomol. Chem. 2011, 9, 2098-2106.
      參考連結參考連結
    23. Wang, D.-W.; Syu, S.; Hung, Y.-T.; Chen, P.; Lee, C. J.; Chen, K.-W.; Chen, Y.-J.; Lin, W.* “Organocatalytic Tandem Three-Component Reaction of Aldehyde, Alkyl Vinyl Ketone, and Amide: One-Pot Syntheses of Highly Functional Alkenes” Org. Biomol. Chem. 2011, 9, 363-366.
      參考連結參考連結
    24. Syu, S.; Wang, D.-W.; Chen, P.; Hung, Y.-T.; Jhang, Y.-W.; Kao, T.-T.; Lee, Y.-T.; Lin, W.*  “Tandem Three-Component Reaction of Aldehyde, Alkyl Acrylate and Amide Using Ethyl Diphenylphosphine as Organocatalyst” Tetrahedron Lett. 2010, 51, 5943-5946.
      參考連結參考連結
    25. Kao, T.-T.; Syu, S.; Jhang, Y.-W.; Lin, W.* "Preparation of Tetrasubstituted Furans via Intramolecular Wittig Reactions with Phosphorus Ylides as Intermediates", Org. Lett. 2010, 12, 3066-3069. 參考連結參考連結
    26. Syu, S.; Kao, T.-T.; Lin, W.* "A New Type of Organocatalyst for Highly Stereoselective Michael Addition of Ketones to Nitroolefins on Water", Tetrahedron 2010, 66, 891–897. 參考連結參考連結
    27. Lin, W.; Chen, L.; Knochel, P.* “Preparation of Functionalized 3,4-Pyridynes via 2-Magnesiated Diaryl Sulfonates”, Tetrahedron 2007, 63, 2787-2797.
    28. Lin, W.; Ilgen, F.; Knochel, P.* “Preparation of Highly Functionalized Arylmagnesium Reagents by the Addition of Magnesium Phenylselenide to Arynes”, Tetrahedron Lett. 2006, 47, 1941-1944.
    29. Lin, W.; Baron, O.; Knochel, P.* “Highly Functionalized Benzene Syntheses by Directed Mono or Multiple Magnesiations with TMPMgCl‧LiCl”, Org. Lett. 2006, 8, 5673-5676.
    30. Sapountzis, I.; Lin, W.; Kofink, C. C.; Despotopoulou, C.; Knochel, P.* “Iron-Catalyzed Aryl-Aryl Cross-Couplings with Magnesium-Derived Copper Reagents”, Angew. Chem. Int. Ed. 2005, 44, 1654-1657. Angew. Chem. 2005, 117, 1682-1685.
    31. Lin, W.; Sapountzis, I.; Knochel, P.* “Preparation of Functionalized Aryl Magnesium Reagents by the Addition of Magnesium Aryl Thiolates and Amides to Arynes”, Angew. Chem. Int. Ed. 2005, 44, 4258-4261. Angew. Chem. 2005, 117, 4330-4333.
    32. Sapountzis, I.; Lin, W.; Fischer, M.; Knochel, P.* “Preparation of Polyfunctional Arynes via 2-Magnesiated Diaryl sulfonates”, Angew. Chem. Int. Ed. 2004, 43, 4364-4366. Angew. Chem. 2004, 116, 4464-4466.
    33. Jang, Y.-J.; Lin, W.-W.; Shih, Y.-K.; Liu, J.-T.; Hwang, M.-H.; Yao, C.-F.* “An Easy One-Pot Method for the Synthesis of 2,2-Disubstituted 1-Nitroalkenes”, Tetrahedron 2003, 59, 4979-4992.
    34. Lin, W.-W.; Jang, Y.-J.; Wang, Y.; Liu, J.-T.; Hu, S.-R.; Wang, L.-Y.; Yao, C.-F.* “An Improved and Easy Method for the Preparation of 2,2-Disubstituted 1-Nitroalkenes”, J. Org. Chem. 2001, 66, 1984-1991.
    35. Liu, J.-T; Lin, W.-W.; Jang, J.-J.; Liu, J.-Y.; Yan, M.-C.; Hung, C.; Kao, K.-H.; Wang, Y.; Yao, C.-F.* “One-pot synthesis of six- or five-membered carbocycles through intramolecular cycloadditions by the use of ethyl chloroformate”, Tetrahedron 1999, 55, 7115-7128.
    36. Yan, M.-C.; Liu, J.-Y.; Lin, W.-W.; Kao, K.-H.; Liu, J.-T; Jang, J.-J.; Yao, C.-F.* “One-Pot Synthesis of Five-Membered Cyclic Thioethers or Ethers via Intramolecular Nitrile Oxide-Olefin Cycloaddition (INOC) or Intramolecular Alkoxycarbonyl Nitronate-Olefin Cycloaddition (IAOC) by the use of Methyl Chloroformate”, Tetrahedron 1999, 55, 12493-12514.
  2. Patent
    1. Knochel, P.; Sapountzis, I; Korn, T.; Lin, W.; Kofink, C. C. 2010,“Iron or Cobalt-Catalyzed Carbon-Carbon Coupling Reaction of Aryls, Alkenes and Alkines with Copper Reagents” European Patent EP1799627 (Publication Number:  WO/2006/040131; International Application No.:  PCT/EP2005/010936; Publication Date: 20.04.2006; International Filing Date: 11.10.2005).
      附件檔案附件檔案 Adobe PDF
    2. Knochel, P.; Sapountzis, I; Korn, T.; Lin, W.; Kofink, C. C. 2008,“Iron or Cobalt-Catalyzed Carbon-Carbon Coupling Reaction of Aryls, Alkenes and Alkines with Copper Reagents” United States Patent US20080269514 (Publication Number:  WO/2006/040131; International Application No.:  PCT/EP2005/010936; Publication Date: 30.10.2008; International Filing Date: 11.10.2005).
      附件檔案附件檔案 Adobe PDF
  3. Others
    1. Ministry of Science and Technology, Academic Research award 參考連結參考連結 附件檔案附件檔案 Adobe PDF
    2.   參考連結參考連結
經歷一覽
服務機關 職稱 部門/系所 擔任職務 起迄年月
National Taiwan Normal UniversityDirectorInstrumentation CenterDirector2014-08 ~
National Taiwan Normal UniversityDistinguished ProfessorDepartment of Chemistry 2014-02 ~
National Taiwan Normal UniversityProfessorDepartment of Chemistry 2014-02 ~
National Taiwan Normal UniversityAssociate ProfessorDepartment of Chemistry 2011-02 ~ 2014-01
National Taiwan Normal UniversityAssistant ProfessorDepartment of Chemistry 2008-02 ~ 2011-01
Technische Universitaet BerlinPostdoctoral ResearchDepartment of Chemistry 2007-01 ~ 2007-12
Ludwig-Maximilians-Universitaet MuenchenPostdoctoral ResearchDepartment of Chemistry 2006-11 ~ 2006-12
National Taiwan Normal UniversityTeaching Assistant (full-time)Department of Chemistry 2002-03 ~ 2003-07
Republic of China Army (obligatory military service)Second Lieutenant  2000-07 ~ 2002-03
學歷一覽
學校名稱 國別 系所 學位 起迄年月
Ludwig-Maximilians-Universitaet MuenchenGermanyDepartment of ChemistryPh.D.2003-08 ~ 2006-11
National Taiwan Normal UniversityTaiwanDepartment of ChemistryM.S.1998-09 ~ 2000-06
National Taiwan Normal UniversityTaiwanDepartment of ChemistryB.S,1994-09 ~ 1998-06
Congratulations一覽
得獎年度 獎項名稱 頒獎單位
2014Outstanding Research Award in 2013National Taiwan Normal University
Off-campus Excellence一覽
得獎年度 獎項名稱 頒獎單位
2013Ta-You Wu Memorial AwardNational Science Council, Taiwan, R.O.C.
2013Outstanding Young Chemist AwardChemical Society Located in Taipei
2013Asian Core Program Lectureship AwardThailand
2011Asian Core Program Lectureship AwardJapan Society for Promotion of Sciences, JSPS
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