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姓名 | 林文偉 |
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Office_Hour | |
實驗室電話 | (02) 77346200 |
辦公室電話 | (02) 77346131 |
傳真 | (02) 2932 4249 |
聯絡地址 | (11677)台北市文山區汀州路四段88號 |
wenweilin@ntnu.edu.tw | |
實驗室網頁 | http://www.chem.ntnu.edu.tw/~wwlin/index.htm |
類別 | 專任師資 |
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職稱 | 教授 |
研究領域 | 不對稱有機催化,新穎反應的開發和雜環化學 |
學術專長 | 不對稱有機催化、有機合成。 |
指導學生 | 博士後研究員:Dr. Lennart Moehlmann, Dr. Ganapuram Madhusudhan Reddy。 博士班:蔡乙鈴, 陳奕儒。 碩士班:楊淑媚, 洪紹豪, 劉孟憲, 蕭明玉, 王建益, 柯紀廷, 張耕華, 謝鎧鴻, 林群凱, 王子平, 張慈修。 |
實驗室 | 有機不對稱催化和雜環化學研究實驗室 / |
學術著作
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- Fan, Y.-S.; Das, U.; Hsiao, M.-Y.; Liu, M.-S.; Lin, W.* "Chemoselective Intramolecular Wittig Reactions for the Synthesis of Oxazoles and Benzofurans” J. Org. Chem. 2014, accepted. 參考連結
- Jang, Y.-J.; Chen, Y.-S.; Lee, C.-J.; Chen, C.-H.; Lin, W.* "Base-Catalyzed Domino Double Michael Reactions of 1-Hydroxy-1,4-dien-3-ones and 2-Alkylidene Malononitirles: A Diastereoselective Route to Polysubstituted 4-Hydroxy-3-keto-cyclohex-3-ene” Synthesis 2014, DOI: 10.1055/s-0034-1379143.
參考連結 - Tsai, Y.-L.; Syu, S.; Yang, S.-M.; Das, U.; Fan, Y.-S.; Lee, C.-J.; Lin, W.* "Synthesis of Multi-Functional Alkenes via Wittig Reaction with a New-Type of Phosphorus Ylides” Tetrahedron 2014, 70, 5038-5045.
參考連結 - Das, U.; Tsai, Y.-L.; Lin, W.* "Preparation of functionalized heteroaromatics using intramolecular Wittig reaction” Org. Biomol. Chem. 2014, 12, 4044-4050. (Perspective) 參考連結
- Lee, C.-J.; Sheu, C.-N.; Tsai, C.-C.; Wu, Z.-Z.; Lin, W.* "Direct β-Acylation of 2-Arylidene-1,3-indandiones with Acyl Chlorides Catalyzed by Organophosphanes” Chem. Commun. 2014, 50, 5304-5306.(Featured in “Emerging investigators” issue 2014) 參考連結
- “Contributors to the Emerging Investigators Issue 2014”, Chem. Commun. 2014, 50, 5100-5114. 參考連結
- Lee, Y.-T.; Das, U.; Chen, Y.-R.; Lee, C.-J.; Chen, C.-H.; Yang, M.-C.; Lin, W.* "Enantioselective Synthesis of Coumarin Derivatives Catalyzed by Primary Amine” Adv. Synth. Catal. 2013, 355, 3154-3160. 參考連結
- Tsai, Y.-L.; Fan, Y.-S.; Lee, C.-J.; Huang, C.-H.; Das, U.; Lin, W.* "An Efficient Synthesis of Trisubstituted Oxazoles via Chemoselective O-Acylations and Intramolecular Wittig Reactions” Chem. Commun. 2013, 49, 10266-10268. 參考連結
- Lee, Y.-T.; Lee, Y.-T.; Lee, C.-J.; Sheu, C.-N.; Lin, B.-Y.; Wang, J.-H.*; Lin, W.* "Chemoselective Synthesis of Tetrasubstituted Furans via Intramolecular Wittig Reactions: Mechanism and Theoretical Analysis” Org. Biomol. Chem. 2013, 11, 5156-5161. 參考連結
- Tsai, Y.-L.; Das, U.; Syu, S.; Lee, C.-J.; Lin, W.* “Facile synthesis of functional tricyclic fused furans via intramolecular Wittig reactions” Eur. J. Org. Chem. 2013, 4634-4641.
參考連結 - Das, U.; Chen, Y.-R.; Tsai, Y.-L.; Lin, W.* “Organocatalytic enantioselective direct vinylogous Michael addition of r-substituted butenolides to 3-aroyl acrylates and 1,2-diaroylethylenes” Chem. Eur. J. 2013, 19, 7713-7717. 參考連結
- Wu, Z.-Z.; Jang, Y.-J.; Lee, C.-J.; Lee, Y.-T.; Lin, W.* “A Versatile and Practical Method for Regioselective Synthesis of Polysubstituted Furanonaphthoquinones” Org. Biomol. Chem. 2013, 11, 828-834. (HOT article) 參考連結
- Das, U.; Tsai, Y.-L.; Lin, W.* “An efficient organocatalytic enantioselective synthesis of spironitrocyclopropanes” Org. Biomol. Chem. 2013, 11, 44-47. (HOT communication) 參考連結
- Lee, Y.-T.; Jang, Y.-J.; Syu, S.; Chou, S.-C.; Lee, C.-J.; Lin, W.* “Preparation of Functional Benzofurans and Indoles via Chemoselective Intramolecular Wittig Reactions” Chem. Commun. 2012, 48, 8135-8137. 參考連結
- Das, U.; Huang, C.-H.; Lin, W.* "Enantioselective synthesis of substituted pyrans via amine-catalyzed Michael addition and subsequent enolization/cyclisation" Chem. Commun. 2012, 48, 5590-5592. (Featured in “Organocatalysis” Web-themed issue) 參考連結
- Lee, C.-J.; Jang, Y.-J.; Wu, Z.-Z. ; Lin, W.* “Preparation of Functional Phosphorus Zwitterions from Activated Alkanes, Aldehydes, and Tributylphosphine: Synthesis of Polysubstituted Furo[3,2-c]coumarins” Org. Lett. 2012, 14, 1906-1909. 參考連結
- Jang, Y.-J.; Syu, S.; Jhang, Y.-W.; Lee, Y.-T.; Lee, C.-J.; Chen, K.-W.; Das, U.; Lin, W.* “Tandem three-component reactions of aldehyde, alkyl acrylate, and dialkylmalonate catalyzed by ethyl diphenylphosphine” Molecules 2012, 17, 2529-2541.參考連結
- Syu, S.; Huang, C.-H.; Chen, K.-W.; Lee, C.-J.; Das, U.; Jang, Y.-J.; Lin, W.* “Enantioselective organocatalytic Michael addition of ketones to alkylidene malonates” Chirality 2012, 24, 600-605.參考連結
- Jang, Y.-J.; Syu, S.; Chen, Y.-J.; Yang, M.-C.; Lin, W.* “Syntheses of Furo[3,4-c]coumarins and Related Furyl Coumarin Derivatives via Intramolecular Wittig Reactions” Org. Biomol. Chem. 2012, 10, 843-847.參考連結
- Syu, S.; Lee, Y.-T.; Jang, Y.-J.; Lin, W.* “Preparation of Functional Benzofurans, Benzothiophenes, and Indoles Using Ester, Thioester, and Amide via Intramolecular Wittig Reactions” Org. Lett. 2011, 13, 2970-2973.參考連結
- Syu, S.; Lee, Y.-T.; Jang, Y.-J.; Lin, W.* “Organocatalytic tandem three-component reaction of imine, alkyl vinyl ketone, and imide via aza-Baylis-Hillman reaction” J. Org. Chem. 2011, 76, 2888-2891.參考連結
- Chen, K.-W.; Syu, S.; Jang, Y.-J.; Lin, W.* “A facile approach to highly functional trisubstituted furans via intramolecular Wittig reactions” Org. Biomol. Chem. 2011, 9, 2098-2106.參考連結
- Wang, D.-W.; Syu, S.; Hung, Y.-T.; Chen, P.; Lee, C. J.; Chen, K.-W.; Chen, Y.-J.; Lin, W.* “Organocatalytic Tandem Three-Component Reaction of Aldehyde, Alkyl Vinyl Ketone, and Amide: One-Pot Syntheses of Highly Functional Alkenes” Org. Biomol. Chem. 2011, 9, 363-366.參考連結
- Syu, S.; Wang, D.-W.; Chen, P.; Hung, Y.-T.; Jhang, Y.-W.; Kao, T.-T.; Lee, Y.-T.; Lin, W.* “Tandem Three-Component Reaction of Aldehyde, Alkyl Acrylate and Amide Using Ethyl Diphenylphosphine as Organocatalyst” Tetrahedron Lett. 2010, 51, 5943-5946.參考連結
- Kao, T.-T.; Syu, S.; Jhang, Y.-W.; Lin, W.* "Preparation of Tetrasubstituted Furans via Intramolecular Wittig Reactions with Phosphorus Ylides as Intermediates", Org. Lett. 2010, 12, 3066-3069. 參考連結
- Syu, S.; Kao, T.-T.; Lin, W.* "A New Type of Organocatalyst for Highly Stereoselective Michael Addition of Ketones to Nitroolefins on Water", Tetrahedron 2010, 66, 891–897. 參考連結
- Lin, W.; Chen, L.; Knochel, P.* “Preparation of Functionalized 3,4-Pyridynes via 2-Magnesiated Diaryl Sulfonates”, Tetrahedron 2007, 63, 2787-2797.
- Lin, W.; Ilgen, F.; Knochel, P.* “Preparation of Highly Functionalized Arylmagnesium Reagents by the Addition of Magnesium Phenylselenide to Arynes”, Tetrahedron Lett. 2006, 47, 1941-1944.
- Lin, W.; Baron, O.; Knochel, P.* “Highly Functionalized Benzene Syntheses by Directed Mono or Multiple Magnesiations with TMPMgCl‧LiCl”, Org. Lett. 2006, 8, 5673-5676.
- Sapountzis, I.; Lin, W.; Kofink, C. C.; Despotopoulou, C.; Knochel, P.* “Iron-Catalyzed Aryl-Aryl Cross-Couplings with Magnesium-Derived Copper Reagents”, Angew. Chem. Int. Ed. 2005, 44, 1654-1657. Angew. Chem. 2005, 117, 1682-1685.
- Lin, W.; Sapountzis, I.; Knochel, P.* “Preparation of Functionalized Aryl Magnesium Reagents by the Addition of Magnesium Aryl Thiolates and Amides to Arynes”, Angew. Chem. Int. Ed. 2005, 44, 4258-4261. Angew. Chem. 2005, 117, 4330-4333.
- Sapountzis, I.; Lin, W.; Fischer, M.; Knochel, P.* “Preparation of Polyfunctional Arynes via 2-Magnesiated Diaryl sulfonates”, Angew. Chem. Int. Ed. 2004, 43, 4364-4366. Angew. Chem. 2004, 116, 4464-4466.
- Jang, Y.-J.; Lin, W.-W.; Shih, Y.-K.; Liu, J.-T.; Hwang, M.-H.; Yao, C.-F.* “An Easy One-Pot Method for the Synthesis of 2,2-Disubstituted 1-Nitroalkenes”, Tetrahedron 2003, 59, 4979-4992.
- Lin, W.-W.; Jang, Y.-J.; Wang, Y.; Liu, J.-T.; Hu, S.-R.; Wang, L.-Y.; Yao, C.-F.* “An Improved and Easy Method for the Preparation of 2,2-Disubstituted 1-Nitroalkenes”, J. Org. Chem. 2001, 66, 1984-1991.
- Liu, J.-T; Lin, W.-W.; Jang, J.-J.; Liu, J.-Y.; Yan, M.-C.; Hung, C.; Kao, K.-H.; Wang, Y.; Yao, C.-F.* “One-pot synthesis of six- or five-membered carbocycles through intramolecular cycloadditions by the use of ethyl chloroformate”, Tetrahedron 1999, 55, 7115-7128.
- Yan, M.-C.; Liu, J.-Y.; Lin, W.-W.; Kao, K.-H.; Liu, J.-T; Jang, J.-J.; Yao, C.-F.* “One-Pot Synthesis of Five-Membered Cyclic Thioethers or Ethers via Intramolecular Nitrile Oxide-Olefin Cycloaddition (INOC) or Intramolecular Alkoxycarbonyl Nitronate-Olefin Cycloaddition (IAOC) by the use of Methyl Chloroformate”, Tetrahedron 1999, 55, 12493-12514.
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- Knochel, P.; Sapountzis, I; Korn, T.; Lin, W.; Kofink, C. C. 2010,“Iron or Cobalt-Catalyzed Carbon-Carbon Coupling Reaction of Aryls, Alkenes and Alkines with Copper Reagents” European Patent EP1799627 (Publication Number: WO/2006/040131; International Application No.: PCT/EP2005/010936; Publication Date: 05.05.2010; International Filing Date: 11.10.2005).附件檔案
- Knochel, P.; Sapountzis, I; Korn, T.; Lin, W.; Kofink, C. C. 2008,“Iron or Cobalt-Catalyzed Carbon-Carbon Coupling Reaction of Aryls, Alkenes and Alkines with Copper Reagents” United States Patent US20080269514 (Publication Number: WO/2006/040131; International Application No.: PCT/EP2005/010936; Publication Date: 30.10.2008; International Filing Date: 11.10.2005).附件檔案
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服務機關 | 職稱 | 部門/系所 | 擔任職務 | 起迄年月 |
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國立臺灣師範大學 | 主任 | 貴重儀器中心 | 中心主任 | 2014年08月 ~ |
國立臺灣師範大學 | 特聘教授 | 化學系 | 2014年02月 ~ | |
國立臺灣師範大學 | 教授 | 化學系 | 2014年02月 ~ | |
國立臺灣師範大學 | 副教授 | 化學系 | 2011年02月 ~ 2014年01月 | |
國立臺灣師範大學 | 助理教授 | 化學系 | 2008年02月 ~ 2011年01月 | |
德國柏林科技大學 | 博士後研究 | 化學所 | 研究員 | 2007年01月 ~ 2007年12月 |
德國慕尼黑大學 | 博士後研究 | 化學所 | 研究員 | 2006年11月 ~ 2006年12月 |
國立臺灣師範大學 | 助教 | 化學系 | 助教 | 2002年03月 ~ 2003年07月 |
陸軍(義務役軍官) | 少尉排長 | 2000年07月 ~ 2002年03月 |
學校名稱 | 國別 | 系所 | 學位 | 起迄年月 |
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德國慕尼黑大學 | 德國 | 化學所 | 博士 | 2003年08月 ~ 2006年11月 |
國立臺灣師範大學 | 臺灣 | 化學系 | 碩士 | 1998年09月 ~ 2000年06月 |
國立臺灣師範大學 | 臺灣 | 化學系 | 理學士 | 1994年09月 ~ 1998年06月 |
得獎年度 | 獎項名稱 | 頒獎單位 |
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2014 | 102年度研究績優獎 | 國立臺灣師範大學 |
得獎年度 | 獎項名稱 | 頒獎單位 |
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2013 | 吳大猷先生紀念獎 | 行政院國家科學委員會 |
2013 | 傑出青年化學獎章 | 中國化學會 |
2013 | Asian Core Program Lectureship Award | Thailand |
2011 | Asian Core Program Lectureship Award | Japan Society for Promotion of Sciences, JSPS |